Solution

Gene detection solution for hereditary deafness

Inputtime:2020-01-15 08:29:20 Views:

Pathogenic factors of hereditary deafness
It is the most common defect of the human sensory and acoustic nervous system caused by the genetic material of parents changed and passed on to the offspring. Whether the parents are single or both deaf patients or healthy carriers, deafness genes will be passed on from parents to their children.

Gene detection solution for hereditary deafness
Gene detection solution for hereditary deafness

 

Product name
Related diseases
Gene detection
Detection sites
Congenital ear gene detection kit
Congenital severe sensorineural deafness
2% - 3% of normal people carry the mutant gene
GJB2
235delC
299-300delAT
176del16bp
512insAACG
PDS gene mutation detection kit
Large vestibular aqueduct syndrome (LVAS)
Congenital or acquired severe sensorineural deafness;
1% - 2% of normal people carry the mutant gene
Autosomal recessive inheritance
IVS7-2A>G
2168A>G
1229C>T
1174A>T
Gene test kit for drug-induced deafness
Drug induced deafness;
3 ‰ normal population carries the mutant gene
SLC26A4(PDS)
1555 A>G
1494C>T

Product advantage
Authoritative and accurate: three types of CFDA registration, 1s013485 certification, S-type amplification curve, 100% consistent with the sequencing results.
Customized screening: the site can be split, prenatal, pregnancy, newborn, hearing-impaired patients and other different groups of targeted testing, more user-friendly.
Comprehensive coverage: 10 loci coverage: hot spot mutations of genes related to congenital otoscopy, delayed otology and drug-induced otodeng.
Simple and fast: the existing fluorescent PCR instrument can detect, with less manual operation, easy to learn and use, high stability, easy to judge, and 1.5 hours to provide the test report.

 

 
 
Intended for
Target Department
Detection cause
Clinical significance
Premarital examination, pregnancy and childbirth examination
Pre pregnancy couples
Maternal
Family history of deafness
Obstetrics and Gynecology Department
Premarital examination body
Medical examination center
Most hereditary deafness is recessive;
More than 5% of normal people carry the gene of deafness
Guide scientific breeding;
Avoid birth of genetically defective children
Newborn hearing screening
Newborn
Obstetrics Department
Neonatal department
Routine hearing screening is easy to miss diagnosis
Patients with delayed and drug-induced deafness cannot be detected
Early diagnosis and early treatment to avoid secondary injury caused by hearing loss
Diagnosis and treatment of hearing impairment
Deaf patients and their families
Cochlear implant operator
 
 
Department of ENT
Cochlear implant is only effective for neuropathic deafness
Most congenital deafness is neural deafness
Predicting the effect of cochlear implant surgery
Medication guidance
Ototoxic drug users
Internal and surgical
Sensitive to aminoglycoside antibiotics in patients with drug-induced deafness
Avoid the tragedy of deafness